Abstract Homologous recombination (HR) is an essential double-stranded DNA break repair pathway.In HR, Rad52 facilitates the formation of Rad51 nucleoprotein filaments on RPA-coated ssDNA.Here, we decipher how Rad52 functions using single-particle cryo-electron microscopy and biophysical approaches.We report that Rad52 is a homodecameric ring and e

Abstract There is little understanding of the Art by Venue effect that reactive oxygen metabolites have on cellular behavior during the processes of invasion and metastasis.These oxygen metabolites could interact with a number of targets modulating their function such as enzymes involved in basement membrane dissolution, adhesion molecules involved

In total, 21 species of bats were found in the Skole Beskids National Nature Park.Among them, six species were recorded in the territory of the Park form the first time: Rhinolophus ferrumequinum, Myotis brandtii, M.alcathoe, M.dasycneme, Plecotus austriacus, and Nyctalus leisleri.Additionally, R.ferrumequinum was recorded in Lviv region for the fi

Early drought stress detection is crucial for restoring productivity, ensuring recovery, and providing vital information for mortality prevention.Hyperspectral remote sensing which is sensitive to subtle changes in leaf constituents and canopy structure is widely used to study how drought stress manifests and evolves over time.Drought impacts are c

Objectives Self-management is a concept frequently used within healthcare but lacks Male Masturbator Accessories consensus.It is the aim of this study to clarify the concept.Design Concept analysis according to Walker and Avant, comprises eight steps: select concept, determine purpose, identify uses, determine defining attributes, identify model ca